Effect of potentially modifiable risk factors associated with. Please click confirm if you are happy to lose these search results. The interheart study found that nine easily measurable and modifiable risk factors could explain over 90 per cent of the risk of a heart attack globally and in all regions and major ethnic groups of the world. Certainly, it is important to acknowledge the limitation that the interheart study defined myocardial. Iqbal r, anand s, ounpuu s, islam s, rangarajan s, yusuf s. Whether lipoproteins are better markers than lipids and lipoproteins for coronary heart disease is widely debated. Transition from metabolic healthy to unhealthy phenotypes and association with cardiovascular disease risk across bmi categories in 90 257 women the nurses health study. The further import of interheart is that its data allow. Objectives to investigate sex differences in risk factors for incident myocardial infarction mi and whether they vary with age. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries the interheart study. Ian brockington seminar the lancet vol 363 january 24, 2004. The operation that you have selected will move away from the current results page, your download options will not persist.
Effects of potentially modifiable risk factors associated with myocardial infarction in 52 countries the interheart study. Svs was involved in the with risk of acute myocardial infarction in 11119 cases and 648 controls from 52 design and, along with sr and ckc, assisted in interpretation and writing the countries the interheart study. In their intriguing analysis of triggering events for acute myocardial infarction within the interheart study population, smyth et al 1 found a relatively high percentage of physical activity and anger or emotional upset. Polycap trial global burden of chd and stroke coronary heart disease. The odds ratios differ from 111 99% ci 0897 for central and eastern europe to 2. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Obesity and the risk of myocardial infarction in 27 000. Physical activity and anger or emotional upset as triggers. Abnormal lipids, smoking, hypertension, diabetes, abdominal obesity, psychosocial factors, consumption of fruits, vegetables, and alcohol, and regular physical activity account for most of the risk of myocardial infarction worldwide in both sexes and at all ages in all regions.
Among adults over 20 yr of age, the estimated prevalence of chd is around 34 per cent in rural areas and 810 per cent in urban areas, representing a twofold rise in rural areas and a sixfold rise in urban areas between the years 1960 and 2000 2. Pure prospective cohort study, and family study not include clinical trials e. An overview of cards collaborative atorvastatin diabetes. Estimating modifiable coronary heart disease risk in. We congratulate annika rosengren and colleagues sept 11, p 9531 on their well done study. Interheart investigators, association of psychosocial risk factors with risk of acute myocardial infarction in 11119 cases and 648 controls from 52 countries the interheart study. Postpartum psychiatric disorders sundspsykologerna. Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes cards overview 1 a multicenter randomized placebo controlled trial to determine hard outcomes of atorvastatin 10mg vs. Vol 364 september 11, 2004 937 effect of potentially modi. Yusuf s1, hawken s, ounpuu s, dans t, avezum a, lanas f, mcqueen m, budaj a, pais p, varigos j, lisheng l. Our aim was to compare the apolipoproteins and cholesterol as indices for risk of acute myocardial infarction. Pdf education and risk for acute myocardial infarction.
Pdf riesgo individual y poblacional en infarto agudo del. However, we think that the need to rely on a selfreported history of hypertension could well. Impact of a genetic risk score on myocardial infarction. Sex differences in risk factors for myocardial infarction. Volume 364, issue 9438 pages 9091010 1117 september 2004 download full issue. There is an enormous amount of literature on psychological stress and cardiovascular disease. Education and risk for acute myocardial infarction in 52. The designated discussant at the european society of cardiology congress, where the results were first reported, lamented mankind is doing a. One of the largest and most important cardiology studies ever. India is undergoing a rapid health transition with rising burden of coronary heart disease chd 1. The most important risk factor by far was cholesteroltwice as important as exercisefollowed by smoking. We congratulate salim yusuf and colleagues sept 11, p 9371 on their carefully done study of risk factors for myocardial infarction in 52 populations worldwide. However, we cannot agree with their statement that the effect of stress on acute myocardial infarction was consistent across different geographic regions. Letter by scherff et al regarding article, physical.
Updated with slides results of the interheart study have shown that nine modifiable risk factors predict more than 90% of acute mi cases. The world health organization estimates that in 2010, coronary heart disease chd will be the leading cause of death globally, causing 30. The results of the interheart study1 show that the factors associated with coronary heart disease are essentially the same wherever in the world people experience an acute myocardial infarction. Effect of potentially modifiable risk factors associated with ami in 52 countries the interheart study. Reports on role of various cardiovascular risk factors in various populations and their. Citations may include links to fulltext content from pubmed central and publisher web sites. Riesgo individual y poblacional en infarto agudo del miocardio.
Interheart a global study of risk factors for acute myocardial infarction. Independent protective effects of fruit and vegetable intake on myocardial infarction in 52 countries. The interheart study was funded by the canadian institutes of health research. We agree that the nine risk factors they studied account for most, if not all, of the populationattributable risk of myocardial infarction. Obesity and the risk of myocardial infarction in 27 000 participants from 52 countries. Pubmed comprises more than 26 million citations for biomedical literature from medline, life science journals, and online books. Interheart is a large, international, standardised, casecontrol study, designed as an initial step to assess. Risk factors for acute myocardial infarction in latin. Request pdf effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries the interheart study. Publications home of jama and the specialty journals of. Association of psychosocial risk factors with risk of acute myocardial infarction in 11119 cases and 648 controls from 52 countries the interheart study. In these analyses of interheart, we confirm previous reports that heavy physical exertion and anger or emotional upset may act as triggers of first acute myocardial infarction, but we also extend findings to all regions of the world. Main outcome measure incident fatal and nonfatal mi. About half of the increase in risk associated with low education was due to modifiable lifestyle factors.
Mcqueen mj, hawken s, wang x, ounpuu s, sniderman a, probstfield j, steyn k, sanderson je, hasani m, volkova e, kazmi k, yusuf s, lipids, lipoproteins, and apolipoproteins as risk markers of myocardial infarction in 52 countries the interheart study. Association of psychosocial risk factors with risk of. Low education was the socioeconomic status marker most consistently associated with increased risk for acute myocardial infarction in this study which comprised 52 countries. Association of psychosocial risk factors with risk of acute myocardial infarction in 11 119 cases and 648 controls from 52 countries the interheart study. As previously described, the interheart study was a casecontrol study of first ami completed in 262 centers across 52 countries. Effect of potentially modifiable risk factors associated. Lipids, lipoproteins, and apolipoproteins as risk markers. Casecontrol study although more than 80% of the global. Potentially modifiable risk factors associated with. The lancet vol 364, issue 9438, pages 9091010 1117. Ysusuf and others published interheart study find, read and cite all the research you need on researchgate.